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1

Genetic susceptibility to type 2 diabetic nephropathy in human and animal models

TOMOHITO GOHDA, MITSUO TANIMOTO, KAORI WATANABE-YAMADA, MASAKAZU MATSUMOTO, SHIGERU KANEKO, SHINJI HAGIWARA, KENJI SHIINA, TOSHIHIDE SHIKE, KAZUHIKO FUNABIKI, YASUHIKO TOMINO

Journal:

Year:

2005

Language:

english

File:

PDF, 64 KB

english, 2005

2

Serum cystatin C may predict the prognostic stages of patients with IgA nephropathy prior to renal biopsy

Yasuhiko Tomino, Shigenobu Suzuki, Tomohito Gohda, Michimasa Kobayashi, Satoshi Horikoshi, Hirokazu Imai, Takao Saito, Tetsuya Kawamura, Noriaki Yorioka, Takashi Harada, Yuichiro Yasumoto, Hiroshi Kid

Journal:

Journal of Clinical Laboratory Analysis

Year:

2001

Language:

english

File:

PDF, 294 KB

english, 2001

3

Significance of serum IgA levels and serum IgA/C3 ratio in diagnostic analysis of patients with IgA nephropathy

Atsuko Maeda, Tomohito Gohda, Kazuhiko Funabiki, Satoshi Horikoshi, Isao Shirato, Yasuhiko Tomino

Journal:

Journal of Clinical Laboratory Analysis

Year:

2003

Language:

english

File:

PDF, 75 KB

english, 2003

4

Peroxisome proliferator-activated receptor γ gene polymorphism is associated with serum triglyceride levels and body mass index in Japanese type 2 diabetic patients

Atsuko Maeda, Tomohito Gohda, Kazuhiko Funabiki, Satoshi Horikoshi, Yasuhiko Tomino

Journal:

Journal of Clinical Laboratory Analysis

Year:

2004

Language:

english

File:

PDF, 95 KB

english, 2004

5

Metabolic impact on serum levels of complement component 3 in Japanese patients

Isao Ohsawa, Hiroyuki Inoshita, Masaya Ishii, Gaku Kusaba, Nobuyuki Sato, Satoshi Mano, Kisara Onda, Tomohito Gohda, Satoshi Horikoshi, Hiroyuki Ohi, Yasuhiko Tomino

Journal:

Journal of Clinical Laboratory Analysis

Year:

2010

Language:

english

File:

PDF, 178 KB

english, 2010

6

Erratum to: Pioglitazone attenuates TGF-β1-induction of fibronectin synthesis and its splicing variant in human mesangial cells via activation of peroxisome proliferator-activated receptor (PPAR) γ [29 (6) 422–428]

Atsuko Maeda, Satoshi Horikoshi, Tomohito Gohda, Toshinao Tsuge, Kunimi Maeda, Yasuhiko Tomino

Journal:

Cell Biology International

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

7

Gene expression profile in diabetic KK/Ta mice

Fan, Qiuling, Shike, Toshihide, Shigihara, Takako, Tanimoto, Mitsuo, Gohda, Tomohito, Makita, Yuichiro, Wang, Li Ning, Horikoshi, Satoshi, Tomino, Yasuhiko

Journal:

Kidney International

Year:

2003

Language:

english

File:

PDF, 126 KB

english, 2003

8

Pioglitazone attenuates TGF-β1-induction of fibronectin synthesis and its splicing variant in human mesangial cells via activation of peroxisome proliferator-activated receptor (PPAR)γ

Atsuko Maeda, Satoshi Horikoshi, Tomohito Gohda, Toshinao Tsuge, Kunimi Maeda, Yasuhiko Tomino

Journal:

Cell Biology International

Year:

2005

Language:

english

File:

PDF, 457 KB

english, 2005

9

Glomerular changes in the KK-Ay/Ta mouse: A possible model for human type 2 diabetic nephropathy

TAKAMICHI ITO, MITSUO TANIMOTO, KAORI YAMADA, SHIGERU KANEKO, MASAKAZU MATSUMOTO, KEIKO OBAYASHI, SHINJI HAGIWARA, MAKI MURAKOSHI, TATSUYA AOKI, MICHIRO WAKABAYASHI, TOMOHITO GOHDA, KAZUHIKO FUNABIKI,

Journal:

Year:

2006

Language:

english

File:

PDF, 686 KB

english, 2006

10

Basic research in progressive glomerulopathies: The role of fibrosing factors in IgA nephropathy and diabetic nephropathy

Tomino, Yasuhiko, Tsuge, Toshinao, Suzuki, Yusuke, Gu, Leyi, Tanimoto, Mitsuo, Gohda, Tomohito, Horikoshi, Satoshi

Journal:

Kidney International

Year:

2005

Language:

english

File:

PDF, 67 KB

english, 2005

11

Predictive Factors Associated with Left Ventricular Hypertrophy at Baseline and in the Follow-Up Period in Non-Diabetic Hemodialysis Patients

Hiroaki Io, Mayumi Matsumoto, Kozue Okumura, Michiko Sato, Atsumi Masuda, Masako Furukawa, Nao Nohara, Mitsuo Tanimoto, Fumiko Kodama, Shinji Hagiwara, Tomohito Gohda, Yoshio Shimizu, Yasuhiko Tomino

Journal:

Seminars in Dialysis

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011

12

Effects of pyridoxamine (K-163) on glucose intolerance and obesity in high-fat diet C57BL/6J mice

Shinji Hagiwara, Tomohito Gohda, Mitsuo Tanimoto, Takamichi Ito, Maki Murakoshi, Ikko Ohara, Takahiko Yamazaki, Masakazu Matsumoto, Satoshi Horikoshi, Kazuhiko Funabiki, Yasuhiko Tomino

Journal:

Year:

2009

Language:

english

File:

PDF, 654 KB

english, 2009

13

Parathyroid hormone gene polymorphism and secondary hyperparathyroidism in hemodialysis patients

Tomohito Gohda, Ichiyu Shou, Mitsumine Fukui, Kazuhiko Funabiki, Satoshi Horikoshi, Isao Shirato, Yasuhiko Tomino

Journal:

American Journal of Kidney Diseases

Year:

2002

Language:

english

File:

PDF, 60 KB

english, 2002

14

Increased serum endogenous secretory receptor for advanced glycation end-product (esRAGE) levels in type 2 diabetic patients with decreased renal function

Tomohito Gohda, Mitsuo Tanimoto, Ju-Young Moon, Hiromichi Gotoh, Tatsuya Aoki, Masakazu Matsumoto, Terumi Shibata, Isao Ohsawa, Kazuhiko Funabiki, Yasuhiko Tomino

Journal:

Diabetes Research and Clinical Practice

Year:

2008

Language:

english

File:

PDF, 168 KB

english, 2008

15

Pleiotropic effect of pyridoxamine on diabetic complications via CD36 expression in KK-Ay/Ta mice

Maki Murakoshi, Mitsuo Tanimoto, Tomohito Gohda, Shinji Hagiwara, Ikko Ohara, Hitoe Toyoda, Yuji Ishikawa, Satoshi Horikoshi, Yasuhiko Tomino

Journal:

Diabetes Research and Clinical Practice

Year:

2009

Language:

english

File:

PDF, 584 KB

english, 2009

16

Altered mouse cholinephosphotransferase gene expression in kidneys of type 2 diabetic KK/TA mouse

Tomohito Gohda, Mitsuo Tanimoto, Kenji Shiina, Takamichi Ito, Michimasa Kobayashi, Shinji Hagiwara, Shigeru Kaneko, Yuichiro Makita, Kazuhiko Funabiki, Satoshi Horikoshi, Yasuhiko Tomino

Journal:

Year:

2004

Language:

english

File:

PDF, 706 KB

english, 2004

17

Effect of pioglitazone on the early stage of type 2 diabetic nephropathy in KK/Ta mice

Mitsuo Tanimoto, Qiuling Fan, Tomohito Gohda, Toshihide Shike, Yuichiro Makita, Yasuhiko Tomino

Journal:

Year:

2004

Language:

english

File:

PDF, 247 KB

english, 2004

18

Effects of eicosapentaenoic acid on the early stage of type 2 diabetic nephropathy in KKAy/Ta mice: involvement of anti-inflammation and antioxidative stress

Minfang Zhang, Shinji Hagiwara, Masukazu Matsumoto, Leyi Gu, Mitsuo Tanimoto, Shinji Nakamura, Shigeru Kaneko, Tomohito Gohda, Jiaqi Qian, Satoshi Horikoshi, Yasuhiko Tomino

Journal:

Year:

2006

Language:

english

File:

PDF, 1.41 MB

english, 2006

19

Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-Ay/Ta mice

Mitsuo Tanimoto, Tomohito Gohda, Shigeru Kaneko, Shinji Hagiwara, Maki Murakoshi, Tatsuya Aoki, Kaori Yamada, Takamichi Ito, Masakazu Matsumoto, Satoshi Horikoshi, Yasuhiko Tomino

Journal:

Year:

2007

Language:

english

File:

PDF, 821 KB

english, 2007

20

Effect of pitavastatin on type 2 diabetes mellitus nephropathy in KK-Ay/Ta mice

Masakazu Matsumoto, Mitsuo Tanimoto, Tomohito Gohda, Tatsuya Aoki, Maki Murakoshi, Kaori Yamada, Takahiko Yamazaki, Shigeru Kaneko, Satoshi Horikoshi, Yasuhiko Tomino

Journal:

Year:

2008

Language:

english

File:

PDF, 641 KB

english, 2008

21

Novel Biomarkers for the Progression of Diabetic Nephropathy: Soluble TNF Receptors

Gohda, Tomohito, Tomino, Yasuhiko

Journal:

Current Diabetes Reports

Year:

2013

Language:

english

File:

PDF, 234 KB

english, 2013

22

Effects of dialysis on the pharmacokinetics of salazosulfapyridine

Yuko Inami, Ken Yamaji, Michiko Sato, Tomohito Gohda…

Journal:

Rheumatology International

Year:

2013

Language:

english

File:

PDF, 292 KB

english, 2013

23

Progressive renal decline as the major feature of diabetic nephropathy in type 1 diabetes

Krolewski, Andrzej S., Gohda, Tomohito, Niewczas, Monika A.

Journal:

Clinical and Experimental Nephrology

Year:

2014

Language:

english

File:

PDF, 682 KB

english, 2014

24

Concomitant use of clopidogrel and proton pump inhibitors may attenuate the prognosis of coronary heart disease in hemodialysis patients

Shimizu, Yoshio, Io, Hiroaki, Hagiwara, Shinji, Gohda, Tomohito, Hamada, Chieko, Horikoshi, Satoshi, Tomino, Yasuhiko

Journal:

Diálisis y Trasplante

Year:

2012

File:

PDF, 441 KB

2012

25

AGE–RAGE interaction and oxidative stress in obesity-related renal dysfunction

Tomino, Yasuhiko, Hagiwara, Shinji, Gohda, Tomohito

Journal:

Kidney International

Year:

2011

Language:

english

File:

PDF, 169 KB

english, 2011

26

Relationship between Abdominal Fat Accumulation and Insulin Resistance in Hemodialysis Patients

GOHDA, Tomohito, GOTOH, Hiromichi, TANIMOTO, Mitsuo, SATO, Michiko, IO, Hiroaki, KANEKO, Kayo, HAMADA, Chieko, TOMINO, Yasuhiko

Journal:

Hypertension Research

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

27

Role of Mindin in Diabetic Nephropathy

Murakoshi, Maki, Gohda, Tomohito, Tanimoto, Mitsuo, Funabiki, Kazuhiko, Horikoshi, Satoshi, Tomino, Yasuhiko

Journal:

Experimental Diabetes Research

Year:

2011

Language:

english

File:

PDF, 474 KB

english, 2011

28

Effect of Exercise on Kidney Function, Oxidative Stress, and Inflammation in Type 2 Diabetic KK- A y Mice

Ishikawa, Yuji, Gohda, Tomohito, Tanimoto, Mitsuo, Omote, Keisuke, Furukawa, Masako, Yamaguchi, Saori, Murakoshi, Maki, Hagiwara, Shinji, Horikoshi, Satoshi, Funabiki, Kazuhiko, Tomino, Yasuhiko

Journal:

Experimental Diabetes Research

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

29

Combination Effects of Enalapril and Losartan on Lipid Peroxidation in the Kidneys of KK-Ay/Ta Mice

Yamazaki, Takahiko, Tanimoto, Mitsuo, Gohda, Tomohito, Ohara, Ikko, Hagiwara, Shinji, Murakoshi, Maki, Matsumoto, Masakazu, Kaneko, Shigeru, Aoki, Tatsuya, Toyoda, Hitoe, Ishikawa, Yuji, Funabiki, Kaz

Journal:

Nephron Experimental Nephrology

Year:

2009

Language:

english

File:

PDF, 767 KB

english, 2009

30

Association of the Cardioankle Vascular Index and Ankle-Brachial Index with Carotid Artery Intima Media Thickness in Hemodialysis Patients

Gohda, Tomohito, Gotoh, Hiromichi, Gotoh, Yoshikazu, Yamaguchi, Saori, Tomino, Yasuhiko

Journal:

International Journal of Nephrology

Year:

2013

Language:

english

File:

PDF, 93 KB

english, 2013

31

Pathogenesis and Treatment of Type 2 Diabetic Nephropathy: Lessons from the Spontaneous KK/Ta Mouse Model

Tomino, Yasuhiko, Tanimoto, Mitsuo, Shike, Toshihide, Shiina, Kenji, Fan, Qiuling, Liao, Jie, Gohda, Tomohito, Makita, Yuichiro, Funabiki, Kazuhiko

Journal:

Current Diabetes Reviews

Year:

2005

Language:

english

File:

PDF, 142 KB

english, 2005

32

Combat Diabetic Nephropathy: From Pathogenesis to Treatment

Gohda, Tomohito, Mima, Akira, Moon, Ju-Young, Kanasaki, Keizo

Journal:

Journal of Diabetes Research

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

33

Effect of the Direct Renin Inhibitor Aliskiren on Urinary Albumin Excretion in Spontaneous Type 2 Diabetic KK- Mouse

Furukawa, Masako, Gohda, Tomohito, Hagiwara, Shinji, Tanimoto, Mitsuo, Horikoshi, Satoshi, Funabiki, Kazuhiko, Tomino, Yasuhiko

Journal:

International Journal of Nephrology

Year:

2013

Language:

english

File:

PDF, 2.90 MB

english, 2013

34

Synergism Between Circulating Tumor Necrosis Factor Receptor 2 and HbA 1c in Determining Renal Decline During 5–18 Years of Follow-up in Patients With Type 1 Diabetes and Proteinuria

Skupien, Jan, Warram, James H., Niewczas, Monika A., Gohda, Tomohito, Malecki, Maciej, Mychaleckyj, Josyf C., Galecki, Andrzej T., Krolewski, Andrzej S.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.37 MB

english, 2014

35

Relationship between Polymorphism in the Angiotensinogen, Angiotensin-Converting Enzyme or Angiotensin II Receptor and Renal Progression in Japanese NIDDM Patients

Tomino, Yasuhiko, Makita, Yuichiro, Shike, Toshihide, Gohda, Tomohito, Haneda, Masakazu, Kikkawa, Ryuichi, Watanabe, Tsuyoshi, Baba, Tsuneharu, Yoshida, Hiroaki

Journal:

Year:

1999

Language:

english

File:

PDF, 270 KB

english, 1999

36

Suppressive Activity of Pemirolast Potassium, an Antiallergic Drug, on Glomerulonephritis

Gohda, Tomohito, Ra, Chisei, Hamada, Chieko, Tsuge, Toshinao, Kawachi, Hiroshi, Tomino, Yasuhiko

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 494 KB

english, 2011

37

Podocyte-specific deletion of Rac1 leads to aggravation of renal injury in STZ-induced diabetic mice

Ishizaka, Masanori, Gohda, Tomohito, Takagi, Miyuki, Omote, Keisuke, Sonoda, Yuji, Trejo, Juan Alejandro Oliva, Asao, Rin, Hidaka, Teruo, Asanuma, Katsuhiko, Horikoshi, Satoshi, Tomino, Yasuhiko

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 2.04 MB

english, 2015

38

The early decline in renal function in patients with type 1 diabetes and proteinuria predicts the risk of end-stage renal disease

Skupien, Jan, Warram, James H, Smiles, Adam M, Niewczas, Monika A, Gohda, Tomohito, Pezzolesi, Marcus G, Cantarovich, Diego, Stanton, Robert, Krolewski, Andrzej S

Journal:

Kidney International

Year:

2012

Language:

english

File:

PDF, 302 KB

english, 2012

39

Effect of Combination Therapy with Angiotensin Receptor Blocker and 1,25-Dihydroxyvitamin D3 in Type 2 Diabetic Nephropathy in KK-Ay/Ta Mice

Ohara, Ikko, Tanimoto, Mitsuo, Gohda, Tomohito, Yamazaki, Takahiko, Hagiwara, Shinji, Murakoshi, Maki, Aoki, Tatsuya, Toyoda, Hitoe, Ishikawa, Yuji, Funabiki, Kazuhiko, Horikoshi, Satoshi, Tomino, Yas

Journal:

Nephron Experimental Nephrology

Year:

2011

Language:

english

File:

PDF, 788 KB

english, 2011

40

Beneficial Effects of Tonsillectomy plus Steroid Pulse Therapy on Inflammatory and Tubular Markers in Patients with IgA Nephropathy

Maruyama, Shuntaro, Gohda, Tomohito, Suzuki, Yusuke, Suzuki, Hitoshi, Sonoda, Yuji, Ichikawa, Saki, Li, Zi, Murakoshi, Maki, Horikoshi, Satoshi, Tomino, Yasuhiko

Journal:

Kidney Research and Clinical Practice

Year:

2016

Language:

english

File:

PDF, 551 KB

english, 2016

41

High serum soluble tumor necrosis factor receptor 1 predicts poor treatment response in acute-stage schizophrenia

Nishimon, Shohei, Ohnuma, Tohru, Takebayashi, Yuto, Katsuta, Narimasa, Takeda, Mayu, Nakamura, Toru, Sannohe, Takahiro, Higashiyama, Ryoko, Kimoto, Ayako, Shibata, Nobuto, Gohda, Tomohito, Suzuki, Yus

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2017

Language:

english

File:

PDF, 407 KB

english, 2017

42

Dilazep Hydrochloride, an Antiplatelet Drug, Inhibits Lipopolysaccharide-Induced Mouse Mesangial Cell IL-6 Secretion and Proliferation

Gohda, Tomohito, Makita, Yuichiro, Shike, Toshihide, Funabiki, Kazuhiko, Shirato, Isao, Tomino, Yasuhiko

Journal:

Kidney & Blood Pressure Research

Year:

2001

Language:

english

File:

PDF, 270 KB

english, 2001

43

Circulating TNF Receptors 1 and 2 Predict Mortality in Patients with End-stage Renal Disease Undergoing Dialysis

Gohda, Tomohito, Maruyama, Shuntaro, Kamei, Nozomu, Yamaguchi, Saori, Shibata, Terumi, Murakoshi, Maki, Horikoshi, Satoshi, Tomino, Yasuhiko, Ohsawa, Isao, Gotoh, Hiromichi, Nojiri, Shuko, Suzuki, Yus

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

44

The Prevalence and Management of Diabetic Nephropathy in Asia

Tomino, Yasuhiko, Gohda, Tomohito

Journal:

Kidney Diseases

Year:

2015

Language:

english

File:

PDF, 622 KB

english, 2015

45

Increase of Urinary Type IV Collagen in Normoalbuminuric Patients with Impaired Glucose Tolerance

Takizawa, Hiroyuki, Satoh, Tomio, Kurusu, Atsushi, Hishiki, Toshimasa, Shike, Toshihide, Gohda, Tomohito, Maeda, Atsuko, Makita, Yuichiro, Suzuki, Shigenobu, Fukui, Mitsumine, Tomino, Yasuhiko

Journal:

Year:

1998

Language:

english

File:

PDF, 209 KB

english, 1998

46

Effect of tonsillectomy with steroid pulse therapy on circulating tumor necrosis factor receptors 1 and 2 in IgA nephropathy

Murakoshi, Maki, Gohda, Tomohito, Sonoda, Yuji, Suzuki, Hitoshi, Tomino, Yasuhiko, Horikoshi, Satoshi, Suzuki, Yusuke

Journal:

Clinical and Experimental Nephrology

Year:

2017

Language:

english

File:

PDF, 667 KB

english, 2017

47

Effect of Calcium Channel Blockers, Nifedipine and Benidipine, on Death of Cultured Mouse Mesangi al Cells

Shike, Toshihide, Tashiro, Kyoichi, Gohda, Tomohito, Funabiki, Kazuhiko, Shirato, Isao, Tomino, Yasuhiko

Journal:

Kidney & Blood Pressure Research

Year:

2000

Language:

english

File:

PDF, 253 KB

english, 2000

48

Clinical predictive biomarkers for normoalbuminuric diabetic kidney disease

Gohda, Tomohito, Nishizaki, Yuji, Murakoshi, Maki, Nojiri, Shuko, Yanagisawa, Naotake, Shibata, Terumi, Yamashita, Mami, Tanaka, Kanako, Yamashita, Yoshinori, Suzuki, Yusuke, Kamei, Nozomu

Journal:

Diabetes Research and Clinical Practice

Year:

2018

Language:

english

File:

PDF, 448 KB

english, 2018

49

Circulating TNF Receptors 1 and 2 Are Associated with the Severity of Renal Interstitial Fibrosis in IgA Nephropathy

Sonoda, Yuji, Gohda, Tomohito, Suzuki, Yusuke, Omote, Keisuke, Ishizaka, Masanori, Matsuoka, Joe, Tomino, Yasuhiko, Abe, Hideharu

Journal:

Year:

2015

Language:

english

File:

PDF, 6.76 MB

english, 2015

50

Pathogenesis and Novel Treatment from the Mouse Model of Type 2 Diabetic Nephropathy

Furukawa, Masako, Gohda, Tomohito, Tanimoto, Mitsuo, Tomino, Yasuhiko

Journal:

The Scientific World JOURNAL

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013